Inositol, sialic acid and fucose metabolism way of Aeromonas hydrophila gas single of pathogenicity of influence
Abstract
[Objective] Investigation inositol, sialic acid and fucose metabolism way in Aeromonas hydrophila gas single of infection host process in bacteria pathogenic of influence. [Methods] The homologous recombinant technology respectively missing Aeromonas hydrophila gas singleNJ-35Strain of Inositol Metabolism Related GeneIolC, Sialic Acid Metabolism Related GeneNanaAnd fucose Metabolism Related GeneFuckDetermination the missing of the zebrafish of half lethal dose(LD50); Will wild strain and missing strains of infection crucian carp statistical wild strain and missing strains in different organization in bacteria load. [Results] The Metabolism Related Gene of missing were success blocking the strain of corresponding substrate of degradation ability.IolCThe lack of lead to strain the zebrafishLD50Increased nearly12Times andNana
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