Expression of IL-1 Family in Immune System
Abstract
The interleukin-1 (IL-1) family is closely related to natural inflammation and immune response. As an important component of innate immunity, IL-1 plays an important role in animals’ organisms. The IL-1 family has 11 cytokines that induce the expression of pro-inflammatory factors and express their proteins through interactions between leukocytes and endothelial cells to regulate the bodys inflammatory response. IL-1 can also respond to non-specific induction of inflammatory cells and regulation of T lymphocytes. However, IL-1 family cytokines lack signal peptides and need a protein to hydrolyze them to activate them into active molecules.In this paper, the members of IL-1 family and the role of IL-1 will be discussed.
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DOI: https://doi.org/10.18686/pas.v2i1.1311
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