The Introduction of the Special Issue Microorganisms are known to produce a plethora of secondary metabolites with a high structural variety and a wide spectrum of biological activity (Newman et al. 2003). Actinobacteria, especially Streptomyces strains, are one of the most importat sources for bioactive natural products with about two-thirds of the antibiotics from natural origin being produced by members out of this genus (Baltz 1998; Weber et al. 2003). However, during the last decades it became increasingly difficult to isolate new actinobacterial strains, producing novel structurally uncommon bioactive substances (Mohr 2016). Additionately, the number of antibiotic resistant strains increased (Cooper and Shlaes 2011), because basing on Davies (2006) “resistance develops within two or three years after the introduction of a new antibiotic treatment” (Mohr 2016). Hence, other microorganisms such as myxobacteria came into focus as producers of bioactive natural products (Clardy et al. 2006; Behal et al. 2003). Actino- as well as myxobacteria are known to live in soil (Dawid 2000; Madigan et al. 2009). This leads to the assumption that they release secondary metabolites to protect themselves as well as their food source against other bacteria and fungi. Unfortunately, it became harder to find new strains using big screening approaches (Balz 2006). Consequently, modern screening approaches have to focus on selected sources from special habitats for the isolation of new bacteria. Hence, this study is dedicated to the isolation of myxobacteria and actinobacteria from Iranian habitats, where both are known to be present (Dawid 2000;Moradi 2016).
The Research Scope of the Special Issue · isolation of special bacteria · identification of rare bacteria · screening of producing antimicrobial bacteria · extraction of their secondary metabolites · purification & finally identification of new active comound
The Article Title of the Special Issue 1: Isolation and Identification of a Myxobacterium Producing Myxovirescins, Myxalamidesand Myxochromids from Intestinal Tract of earth Worm of Ghaemshahr County 2: 1- Corallococcus chalusensis sp. nov., a myxobacterium isolated from soil sample of Iran, 3: Structurally Diverse Metabolites from the rare Actinobacterium Saccharothrix xinjiangensis 4: A new effective method for DNA extraction of Actinobacteria 5: Isolation and Antifungal and Antimycobacterium Activities ofNew derivative of Staurosporine from Streptomyces sp Strain Act4Zk 6: Nocardiopsis sinuspersici sp. nov, isolated fromsandy rhizospheric soil 7: Nannocystis konarekensis sp. nov., a novel myxobacterium froman Iranian desert Submission guidelines
All papers should be submitted via the Probe - Microbiology submission system: http://probe.usp-pl.com/index.php/PM Submitted articles should not be published or under review elsewhere. All submissions will be subject to the journal’s standard peer review process. Criteria for acceptance include originality, contribution, scientific merit and relevance to the field of interest of the Special Issue. Important Dates Paper Submission Due: December 30 ,2019
The Lead Guest Editor Zahra Khosravi Babadi |
