Nuclear Magnetic Resonance residual dipolar coupling parameters in organic molecular structure identification in Application

Abstract

 Residual dipolar Coupling(Residuals dipolar coupling RDC)As an Nuclear Magnetic Resonance the to the opposite sex parameters in analysis organic molecular configuration and advantage conformation and other aspects of application has strong of advantageIt can reflect molecular Central Plains sub-in Magnetic Field in space distance and angle informationMolecular three-dimensional space of Construction.This paper on residual dipolar coupling in organic molecular structure identification of Progress ReviewDetailed summary the determinationRDCOf directional medium and detection analysis methodsAnd use instance showRDCIn natural product, synthesis drug, organic reaction intermediate or complexAnd the mapping isomers and stereo chemical aspects of Analysis and Application.